SCHEMBL21149237

SCHEMBL21149237

c1ccc2cc(-c3nc(-c4ccc5sc6ccccc6c5c4)nc(-c4cccc5sc6ccccc6c45)n3)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
S1PR5 Q9H228 8/20 0.38
S1PR4 O95977 6/20 0.38
ALOX5 P09917 1/20 0.36
GPR3 P46089 1/20 0.35
PIM1 P11309 1/20 0.34
CYP1A2 P05177 2/20 0.33
GSTP1 P09211 1/20 0.33
BRDT Q58F21 1/20 0.32
APP P05067 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
AURKA O14965 1/20 0.32
AURKB Q96GD4 1/20 0.32
PTPN7 P35236 1/20 0.32
DUSP3 P51452 1/20 0.32
PTPN12 Q05209 1/20 0.32
PTPN22 Q9Y2R2 1/20 0.32
RAC1 P63000 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21148232 0.95 S1PR5 (0.40) S1PR5S1PR4ALOX5GPR3PIM1
SCHEMBL24266824 0.95 S1PR5 (0.40) S1PR5S1PR4ALOX5GPR3PIM1
SCHEMBL21148613 0.94 GPR3 (0.40) ALOX5GPR3CYP1A2BRDTAPP
SCHEMBL21149207 0.93 S1PR5 (0.38) S1PR5S1PR4ALOX5GPR3PIM1
SCHEMBL24344290 0.91 S1PR5 (0.39) S1PR5S1PR4ALOX5GPR3PIM1
SCHEMBL23920394 0.91 S1PR5 (0.38) S1PR5S1PR4ALOX5PIM1CYP1A2
SCHEMBL21149215 0.91 S1PR5 (0.38) S1PR5S1PR4ALOX5PIM1CYP1A2
SCHEMBL24239105 0.91 ALOX5 (0.37) S1PR5S1PR4ALOX5PIM1CYP1A2
SCHEMBL26448301 0.90 S1PR5 (0.36) S1PR5S1PR4ALOX5PIM1GSTP1
SCHEMBL21109252 0.90 S1PR5 (0.40) S1PR5S1PR4ALOX5PIM1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 S1PR5 3651/4885S1PR4 3107/4885ALOX5 306/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 S1PR5 3651/4885S1PR4 3107/4885ALOX5 306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.