Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5240209 | 0.79 | ABCC9 (0.39) | PDE4APDE4BPDE4CPDE4DPARP1 | |
| SCHEMBL21009725 | 0.73 | HTR2A (0.33) | PDE4APDE4BPDE4CPDE4DSRD5A1 | |
| SCHEMBL14559239 | 0.71 | SLC6A4 (0.42) | PARP1PARP2HDAC2 | |
| SCHEMBL14559235 | 0.70 | ALDH1A1 (0.42) | TP53 | |
| SCHEMBL3584879 | 0.64 | DDB1 (0.52) | PDE4APDE4BPDE4CPDE4DIKBKB | |
| SCHEMBL16796843 | 0.64 | DDB1 (0.52) | PDE4APDE4BPDE4CPDE4DIKBKB | |
| SCHEMBL8177567 | 0.64 | DDB1 (0.52) | PDE4APDE4BPDE4CPDE4DIKBKB | |
| SCHEMBL22042642 | 0.63 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DPARP1 | |
| SCHEMBL14458003 | 0.62 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL14458008 | 0.62 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135600-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |