Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21148980 | 0.79 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DPARP1 | |
| SCHEMBL14559239 | 0.71 | SLC6A4 (0.42) | MEN1KMT2AHTR2AHTR2CPARP1 | |
| SCHEMBL14559235 | 0.70 | ALDH1A1 (0.42) | ALDH1A1MEN1RAB9AKMT2AGAA | |
| SCHEMBL21009725 | 0.70 | HTR2A (0.33) | ALDH1A1KMT2AGAAPDE4APDE4B | |
| SCHEMBL22201147 | 0.69 | PDE4A (0.44) | ALDH1A1LMNAMEN1KMT2AGAA | |
| SCHEMBL482061 | 0.69 | PDE4A (0.44) | ALDH1A1LMNAMEN1KMT2AGAA | |
| SCHEMBL4142288 | 0.69 | PDE4A (0.44) | ALDH1A1LMNAMEN1KMT2AGAA | |
| SCHEMBL14480813 | 0.68 | — | — | |
| SCHEMBL22201156 | 0.68 | DDB1 (0.44) | ABCC9ABCC8KCNJ11KCNJ8ALDH1A1 | |
| SCHEMBL18341407 | 0.68 | DDB1 (0.44) | ABCC9ABCC8KCNJ11KCNJ8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366043-B1 | 2-HETEROARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2007-06-20 | — | — | EP | disclosed |
| CN-1319965-C | 2-heteroaryl-3, 4-dihydro-2H-pyrrole derivatives and their use as pesticides | BAYER CROP SCIENCE AG (DE) | 2007-06-06 | — | — | CN | disclosed |
| US-7186722-B2 | 2-heteroaryl-3,4-dihydro-2h-pyrrole derivatives and the use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-03-06 | — | — | US | disclosed |
| US-7186722-B2 | 2-heteroaryl-3,4-dihydro-2h-pyrrole derivatives and the use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-03-06 | — | — | US | disclosed |
| US-7186722-B2 | 2-heteroaryl-3,4-dihydro-2h-pyrrole derivatives and the use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-03-06 | — | — | US | disclosed |
| CN-1531534-A | 2-heteroaryl-3,4-dihydro-2H-pyrrole derivatives and use thereof as pesticides | �ݶ�ũ�����ѧ�ɷݹ�˾ | 2004-09-22 | — | — | CN | disclosed |
| US-20040116477-A1 | 2-Heteroaryl-3,4-dihydro-2h-pyrrole derivatives and the use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2004-06-17 | — | — | US | disclosed |
| EP-1366043-A1 | 2-HETEROARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | Bayer CropScience AG (DE) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002064588-A1 | 2-HETEROARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-08-22 | — | — | WO | disclosed |