SCHEMBL21149221

SCHEMBL21149221

c1cc(-c2nc(-c3ccc(-c4ccc5ccccc5c4)cc3)nc(-c3cccc4ccccc34)n2)cc(-c2cccc3oc4ccccc4c23)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
KDM4E B2RXH2 5/20 0.39
HSD17B10 Q99714 5/20 0.39
MAPT P10636 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
HPGD P15428 3/20 0.39
TP53 P04637 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 2/20 0.39
MAPK1 P28482 2/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
PLA2G2A P14555 1/20 0.37
PLA2G4A P47712 1/20 0.37
PIM1 P11309 2/20 0.37
CYP1A2 P05177 2/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26231355 0.95 ALDH1A1 (0.40) ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2
SCHEMBL21148465 0.95 PIM1 (0.38) ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2
SCHEMBL23820730 0.95 PLA2G2A (0.40) ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2
SCHEMBL26271241 0.94 ALDH1A1 (0.39) ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2
SCHEMBL21149218 0.94 ALDH1A1 (0.42) ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2
SCHEMBL21148507 0.94 ALDH1A1 (0.42) ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2
SCHEMBL26260396 0.94 PIM1 (0.39) ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2
SCHEMBL25505257 0.93 PLA2G2A (0.36) ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2
SCHEMBL23820367 0.93 ALDH1A1 (0.39) ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2
SCHEMBL26271145 0.93 HCRTR1 (0.38) ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 ALDH1A1 191/4885KDM4E 4500/4885HSD17B10 1380/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 ALDH1A1 191/4885KDM4E 4500/4885HSD17B10 1380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.