SCHEMBL24344290

SCHEMBL24344290

c1ccc2cc(-c3nc(-c4ccc5ccccc5c4)nc(-c4cccc5cccc(-c6ccc7sc8ccccc8c7c6)c45)n3)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR5 Q9H228 9/20 0.39
S1PR4 O95977 7/20 0.39
ALOX5 P09917 1/20 0.38
GSTP1 P09211 1/20 0.35
GPR3 P46089 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PIM1 P11309 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
CYP1A2 P05177 2/20 0.32
DHFR P00374 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24344291 0.96 S1PR5 (0.40) S1PR5S1PR4ALOX5GSTP1GPR3
SCHEMBL24342536 0.93 S1PR5 (0.39) S1PR5S1PR4ALOX5GSTP1GPR3
SCHEMBL23822239 0.92 S1PR5 (0.40) S1PR5S1PR4ALOX5GSTP1GPR3
SCHEMBL21149237 0.91 S1PR5 (0.38) S1PR5S1PR4ALOX5GSTP1GPR3
SCHEMBL27251257 0.90 S1PR5 (0.35) S1PR5S1PR4ALOX5GPR3ALDH1A1
SCHEMBL24342506 0.90 S1PR5 (0.40) S1PR5S1PR4ALOX5GSTP1ALDH1A1
SCHEMBL24343281 0.88 S1PR5 (0.43) S1PR5S1PR4ALOX5GSTP1GPR3
SCHEMBL23385477 0.87 S1PR5 (0.40) S1PR5S1PR4ALOX5GSTP1GPR3
SCHEMBL26435406 0.87 F9 (0.36) S1PR5S1PR4ALOX5GPR3ALDH1A1
SCHEMBL24266849 0.87 GPR3 (0.45) S1PR5S1PR4GSTP1GPR3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-12-01 US disclosed
US-20220123233-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220123233-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, LIMS1, MAL2 S1PR5 2870/4885S1PR4 1668/4885ALOX5 802/4885
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, PIEZO1, LIMS1 S1PR5 3611/4885S1PR4 2933/4885ALOX5 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.