SCHEMBL21149254

SCHEMBL21149254

c1cc(-c2ccc3ccccc3c2)cc(-c2nc(-c3cccc4oc5ccccc5c34)nc(-c3cccc4oc5ccccc5c34)n2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
PLA2G2A P14555 2/20 0.39
PLA2G4A P47712 2/20 0.39
ALDH1A1 P00352 5/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
HSD17B10 Q99714 4/20 0.38
KDM4E B2RXH2 3/20 0.38
TP53 P04637 3/20 0.38
CYP1A2 P05177 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP17A1 P05093 1/20 0.38
CYP19A1 P11511 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
MAPT P10636 3/20 0.38
PLA2G10 O15496 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26231357 0.99 PLA2G2A (0.41) HSD17B1HSD17B2PLA2G2APLA2G4AALDH1A1
SCHEMBL26231402 0.99 PLA2G2A (0.41) HSD17B1HSD17B2PLA2G2APLA2G4AALDH1A1
SCHEMBL27252327 0.97 ALDH1A1 (0.43) HSD17B1HSD17B2PLA2G2APLA2G4AALDH1A1
SCHEMBL26260471 0.97 PLA2G2A (0.40) HSD17B1HSD17B2PLA2G2APLA2G4AALDH1A1
SCHEMBL26231359 0.97 PLA2G2A (0.40) HSD17B1HSD17B2PLA2G2APLA2G4AALDH1A1
SCHEMBL23822680 0.97 PLA2G2A (0.40) HSD17B1HSD17B2PLA2G2APLA2G4AALDH1A1
SCHEMBL25817826 0.97 ALDH1A1 (0.43) HSD17B1HSD17B2PLA2G2APLA2G4AALDH1A1
SCHEMBL26260468 0.97 HSD17B1 (0.38) HSD17B1HSD17B2ALDH1A1SMN1; SMN2HSD17B10
SCHEMBL24372504 0.96 ALDH1A1 (0.42) HSD17B1HSD17B2PLA2G2APLA2G4AALDH1A1
SCHEMBL24655167 0.96 ALDH1A1 (0.42) HSD17B1HSD17B2PLA2G2APLA2G4AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 HSD17B1 1348/4885HSD17B2 1213/4885PLA2G2A 1762/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 HSD17B1 1348/4885HSD17B2 1213/4885PLA2G2A 1762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.