Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24974635 | 0.80 | HDAC3 (0.43) | DCUN1D1TSHRHDAC3HDAC1HDAC2 | |
| SCHEMBL21150824 | 0.79 | DCUN1D1 (0.44) | DCUN1D1KMT2AALDH1A1POLBNPY1R | |
| SCHEMBL21151185 | 0.76 | HDAC1 (0.41) | ALDH1A1NPY1RMAPTLMNAHTT | |
| SCHEMBL24974685 | 0.74 | KMT2A (0.37) | KMT2A | |
| SCHEMBL21151173 | 0.72 | TACR1 (0.47) | KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL21150801 | 0.69 | L3MBTL1 (0.54) | KMT2AALDH1A1NPY1RDRD2LMNA | |
| SCHEMBL5613044 | 0.67 | KMT2A (0.57) | KMT2AALDH1A1POLBMAPTLMNA | |
| SCHEMBL5612905 | 0.67 | METAP2 (0.61) | ALDH1A1MAPTHTTTSHRSMN1; SMN2 | |
| SCHEMBL24216689 | 0.67 | MAP4K4 (0.50) | KMT2AALDH1A1POLBMAPTTSHR | |
| SCHEMBL24027900 | 0.66 | CYP2C19 (0.46) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |