SCHEMBL21150801

SCHEMBL21150801

CC(C)(C)OC(=O)NC1CC2(C1)NC(=O)N(Cc1ccccc1)C2=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.54
KMT2A Q03164 2/20 0.54
NPC1 O15118 1/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
EPHX2 P34913 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP2C19 P33261 2/20 0.41
KDM1A O60341 1/20 0.41
MAOB P27338 1/20 0.41
KCNA3 P22001 1/20 0.41
MAPK8 P45983 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40
HDAC6 Q9UBN7 2/20 0.40
AKT1 P31749 1/20 0.40
NPY1R P25929 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21151305 0.81 EPHX2 (0.46) L3MBTL1KMT2ALMNAEPHX2KDM1A
SCHEMBL21151306 0.78 GAA (0.44) L3MBTL1KMT2AEPHX2KDM1AMAOB
SCHEMBL8569334 0.77 KMT2A (0.58) L3MBTL1KMT2AEPHX2ALDH1A1KDM1A
SCHEMBL29048164 0.76 SMN1; SMN2 (0.57) L3MBTL1KMT2AALDH1A1CYP2C19NPY1R
SCHEMBL3245801 0.76 KMT2A (0.56) L3MBTL1KMT2ANPC1LMNAHTT
SCHEMBL1815532 0.75 KMT2A (0.65) L3MBTL1KMT2AEPHX2KDM1AMAOB
SCHEMBL5314188 0.74 KMT2A (0.54) KMT2ANPC1LMNAHTTRAB9A
SCHEMBL6865331 0.74 KMT2A (0.60) L3MBTL1KMT2ANPC1LMNAHTT
SCHEMBL5425216 0.74 KMT2A (0.60) L3MBTL1KMT2ANPC1LMNAHTT
SCHEMBL25573668 0.73 KMT2A (0.51) L3MBTL1KMT2AEPHX2KDM1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572370-B2 CD16A binding agents and uses thereof BIOHAVEN THERAPEUTICS LTD. (US) 2023-02-07 US disclosed
WO-2019136442-A1 CD16A BINDING AGENTS AND USES THEREOF KLEO PHARMACEUTICALS, INC. (US) 2019-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572370-B2 CD16A binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B L3MBTL1 1544/4885KMT2A 499/4885NPC1 1745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.