SCHEMBL21150898

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21150135	0.94	ALK (0.64)	ALKMAPK7BRD4INSRROS1
	SCHEMBL19921077	0.89	MAPK7 (0.54)	ALKMAPK7BRD4INSRROS1
	SCHEMBL21099619	0.88	LRRK2 (0.53)	ALKMAPK7BRD4INSRIGF1R
	SCHEMBL21150649	0.86	ALK (0.52)	ALKMAPK7INSRROS1BMPR1B
	SCHEMBL19867338	0.83	ALK (0.71)	ALKMAPK7INSRROS1BMPR1B
	SCHEMBL19921103	0.82	ALK (0.78)	ALKMAPK7BRD4INSRROS1
	SCHEMBL12729305	0.82	ALK (0.61)	ALKMAPK7INSRROS1BMPR1B
	SCHEMBL21099488	0.81	ALK (0.73)	ALKMAPK7INSRROS1BMPR1B
	SCHEMBL21150935	0.81	ALK (0.82)	ALKMAPK7INSRROS1BMPR1B
	SCHEMBL21099617	0.81	LRRK2 (0.53)	ALKMAPK7BRD4INSREGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.