Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.53 |
| ▸ | MAPK7 | Q13164 | 7/20 | 0.53 |
| ▸ | BRD4 | O60885 | 5/20 | 0.53 |
| ▸ | BRDT | Q58F21 | 3/20 | 0.53 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 2/20 | 0.45 |
| ▸ | IGF1R | P08069 | 2/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099617 | 0.93 | LRRK2 (0.53) | LRRK2MAPK7BRD4BRDTDCLK1 | |
| SCHEMBL19921121 | 0.89 | LRRK2 (0.52) | LRRK2MAPK7BRD4BRDTDCLK1 | |
| SCHEMBL21150898 | 0.88 | ALK (0.56) | LRRK2MAPK7BRD4BRDTDCLK1 | |
| SCHEMBL19921183 | 0.82 | LRRK2 (0.54) | LRRK2MAPK7BRD4BRDTDCLK1 | |
| SCHEMBL21099501 | 0.82 | ALK (0.52) | INSRIGF1RALKPTK2 | |
| SCHEMBL21150135 | 0.81 | ALK (0.64) | LRRK2MAPK7BRD4BRDTDCLK1 | |
| SCHEMBL21099489 | 0.80 | ALK (0.54) | LRRK2MAPK7BRD4BRDTDCLK1 | |
| SCHEMBL21099658 | 0.80 | ALK (0.60) | LRRK2MAPK7DCLK1INSRIGF1R | |
| SCHEMBL19921077 | 0.77 | MAPK7 (0.54) | LRRK2MAPK7BRD4BRDTDCLK1 | |
| SCHEMBL21099498 | 0.76 | ALK (0.60) | LRRK2MAPK7DCLK1INSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498716-A1 | THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS | Hongyun Biotech Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |