Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.41 |
| ▸ | USP2 | O75604 | 8/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21151258 | 0.90 | CACNA1H (0.49) | ALDH1A1HIF1ACYP2D6HSD17B10CYP3A4 | |
| SCHEMBL21151021 | 0.89 | USP2 (0.46) | ALDH1A1HIF1ACYP2D6HSD17B10CYP3A4 | |
| SCHEMBL21151202 | 0.87 | HIF1A (0.55) | ALDH1A1HIF1ACYP2D6HSD17B10CYP3A4 | |
| SCHEMBL21150844 | 0.84 | CYP3A4 (0.45) | ALDH1A1HIF1ACYP2D6HSD17B10CYP3A4 | |
| SCHEMBL24974458 | 0.84 | HIF1A (0.52) | ALDH1A1HIF1ACYP2D6HSD17B10CYP3A4 | |
| SCHEMBL21151791 | 0.83 | TACR1 (0.44) | ALDH1A1HIF1ACYP2D6HSD17B10CYP3A4 | |
| SCHEMBL21150855 | 0.83 | CYP3A4 (0.45) | ALDH1A1HIF1ACYP2D6HSD17B10CYP3A4 | |
| SCHEMBL21151919 | 0.82 | CACNA1H (0.44) | ALDH1A1HIF1ACYP2D6HSD17B10CYP3A4 | |
| SCHEMBL21151309 | 0.82 | RAB9A (0.42) | ALDH1A1HIF1ACYP2D6HSD17B10CYP3A4 | |
| SCHEMBL21151313 | 0.81 | HIF1A (0.44) | ALDH1A1HIF1ACYP2D6HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572370-B2 | CD16A binding agents and uses thereof | BIOHAVEN THERAPEUTICS LTD. (US) | 2023-02-07 | — | — | US | disclosed |
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572370-B2 | CD16A binding agents and uses thereof | FCGR1A, FCGR2A, FCGR3B | ALDH1A1 1203/4885HIF1A 1669/4885CYP2D6 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.