SCHEMBL21151272

SCHEMBL21151272

O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCn1cc(-c2cccc(NC(=O)N3CCC4(CC3)NC(=O)N(c3cccc(-n5cnnn5)c3)C4=O)c2)nn1)ON1C(=O)CCC1=O

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ NAMPT P43490 2/20 0.32
▸ KMT2A Q03164 3/20 0.32
▸ TP53 P04637 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ ITGB3 P05106 1/20 0.30
▸ ITGA2B P08514 1/20 0.30
▸ TACR1 P25103 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21151259 0.91 NAMPT (0.34) NAMPTKMT2AMEN1TACR1
SCHEMBL24974548 0.89 KMT2A (0.37) MAPK1RAB9ANAMPTKMT2ATP53
SCHEMBL21151158 0.89 NAMPT (0.33) NAMPTTACR1
SCHEMBL21150845 0.89 NAMPT (0.34) NAMPTITGB3ITGA2BTACR1
SCHEMBL21151201 0.88 MCHR1 (0.38) MAPK1NAMPT
SCHEMBL21152140 0.88 ENPP2 (0.35) NAMPTTACR1
SCHEMBL21150858 0.88 NAMPT (0.36) NAMPT
SCHEMBL21150848 0.87 NAMPT (0.34) NAMPTITGB3ITGA2BTACR1
SCHEMBL24974528 0.87 MAPK1 (0.33) MAPK1NAMPTITGB3ITGA2BTACR1
SCHEMBL21151783 0.86 NAMPT (0.33) MAPK1NAMPTTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572370-B2 CD16A binding agents and uses thereof BIOHAVEN THERAPEUTICS LTD. (US) 2023-02-07 — — US disclosed
WO-2019136442-A1 CD16A BINDING AGENTS AND USES THEREOF KLEO PHARMACEUTICALS, INC. (US) 2019-07-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572370-B2 CD16A binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B MAPK1 3778/4885RAB9A 2444/4885NAMPT 1356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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