Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19534073 | 0.83 | POLB (0.50) | POLBIDO1TDO2EGLN1EGLN3 | |
| SCHEMBL19534078 | 0.83 | POLB (0.54) | POLBIDO1TDO2EGLN1EGLN3 | |
| SCHEMBL13879542 | 0.82 | POLB (0.65) | POLBIDO1TDO2EGLN1EGLN3 | |
| SCHEMBL22256978 | 0.79 | POLB (0.50) | POLBIDO1TDO2EGLN1EGLN3 | |
| SCHEMBL19534278 | 0.79 | POLB (0.53) | POLBIDO1TDO2EGLN1EGLN3 | |
| SCHEMBL21150857 | 0.73 | POLB (0.46) | POLBIDO1TDO2EGLN1EGLN3 | |
| SCHEMBL19534281 | 0.72 | GPR119 (0.51) | POLBITGB3ITGA2BTACR1KMT2A | |
| SCHEMBL21151219 | 0.71 | POLB (0.44) | POLBIDO1TDO2NPC1RAB9A | |
| SCHEMBL21150773 | 0.71 | ITGB3 (0.47) | POLBIDO1TDO2EGLN1EGLN3 | |
| SCHEMBL2121329 | 0.70 | EGLN1 (0.62) | POLBEGLN1EGLN3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |