SCHEMBL21150773

SCHEMBL21150773

O=C(O)CCS(=O)(=O)N1CCC2(CC1)NC(=O)N(c1ccccc1)C2=O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 2/20 0.47
ITGA2B P08514 2/20 0.47
EGLN1 Q9GZT9 3/20 0.40
EGLN3 Q9H6Z9 2/20 0.40
POLB P06746 2/20 0.39
IDO1 P14902 1/20 0.39
TDO2 P48775 1/20 0.39
LMNA P02545 1/20 0.37
TACR1 P25103 3/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21150772 0.85 ITGB3 (0.38) ITGB3ITGA2BEGLN1EGLN3POLB
SCHEMBL24974538 0.84 SLC6A9 (0.44) ITGB3ITGA2BLMNA
SCHEMBL21151112 0.81 KMT2A (0.56) LMNATACR1NPC1RAB9A
SCHEMBL19534078 0.72 POLB (0.54) ITGB3ITGA2BEGLN1EGLN3POLB
SCHEMBL19534073 0.72 POLB (0.50) ITGB3ITGA2BEGLN1EGLN3POLB
SCHEMBL13879542 0.71 POLB (0.65) EGLN1EGLN3POLBIDO1TDO2
SCHEMBL21152145 0.71 POLB (0.49) ITGB3ITGA2BEGLN1EGLN3POLB
SCHEMBL2121329 0.71 EGLN1 (0.62) ITGB3ITGA2BEGLN1EGLN3POLB
SCHEMBL24974651 0.70 MT-CO2 (0.45) POLBLMNAGAA
SCHEMBL21150757 0.69 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572370-B2 CD16A binding agents and uses thereof BIOHAVEN THERAPEUTICS LTD. (US) 2023-02-07 US disclosed
WO-2019136442-A1 CD16A BINDING AGENTS AND USES THEREOF KLEO PHARMACEUTICALS, INC. (US) 2019-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572370-B2 CD16A binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B ITGB3 77/4885ITGA2B 35/4885EGLN1 4635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.