SCHEMBL21152287

SCHEMBL21152287

CC(C)(C)[Si](C)(C)OC[C@]1(CO)COCC[C@H](n2ccc(=O)[nH]c2=O)O1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ DUT P33316 5/20 0.45
▸ SLC28A1 O00337 1/20 0.35
▸ SLC28A2 O43868 1/20 0.35
▸ SLC29A1 Q99808 1/20 0.35
▸ SLC28A3 Q9HAS3 1/20 0.35
▸ P2RY6 Q15077 1/20 0.34
▸ P2RY14 Q15391 4/20 0.33
▸ P2RY2 P41231 2/20 0.32
▸ P2RY4 P51582 2/20 0.32
▸ NT5E P21589 1/20 0.32
▸ ENTPD2 Q9Y5L3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22666153 0.89 DUT (0.48) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL20879386 0.84 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL20879436 0.81 DUT (0.48) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL25567944 0.79 DUT (0.46) DUTP2RY6
SCHEMBL22666158 0.78 DUT (0.43) DUT
SCHEMBL23244019 0.77 SLC28A1 (0.36) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL23069416 0.77 SLC28A1 (0.36) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL25398106 0.77 DUT (0.46) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL26273364 0.77 DUT (0.46) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL24928459 0.77 DUT (0.49) DUTSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019136180-A2 HETERODUPLEX NUCLEIC ACID MOLECULES AND USES THEREOF AVIDITY BIOSCIENCES LLC (US) 2019-07-11 — — WO disclosed
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