Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21285324 | 0.88 | IDO1 (0.33) | CYP19A1IDO1 | |
| SCHEMBL21480920 | 0.86 | IDO1 (0.35) | IDO1 | |
| SCHEMBL18790863 | 0.80 | IDO1 (0.34) | CYP19A1IDO1 | |
| SCHEMBL14023217 | 0.80 | GPR84 (0.35) | CYP19A1GPR84 | |
| SCHEMBL24849931 | 0.79 | CYP19A1 (0.35) | CYP19A1GPR84 | |
| SCHEMBL21953543 | 0.75 | CYP19A1 (0.38) | CYP19A1GPR84KDRALDH1A1CYP2C19 | |
| SCHEMBL24837415 | 0.74 | NOTUM (0.32) | IDO1 | |
| SCHEMBL23553779 | 0.73 | ACHE (0.33) | IDO1 | |
| SCHEMBL23192059 | 0.72 | IDO1 (0.32) | IDO1 | |
| SCHEMBL19705751 | 0.72 | CYP19A1 (0.61) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254705-B2 | Cyclic peptide analogs and conjugates thereof | SIRENAS LLC (US) | 2022-02-22 | — | — | US | disclosed |
| US-20190211060-A1 | CYCLIC PEPTIDE ANALOGS AND CONJUGATES THEREOF | SIRENAS LLC (US) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190211060-A1 | CYCLIC PEPTIDE ANALOGS AND CONJUGATES THEREOF | VIP, NGLY1, GRPR | CYP19A1 1525/4885GPR84 1082/4885OPRM1 2150/4885 |
| US-11254705-B2 | Cyclic peptide analogs and conjugates thereof | VIP, NGLY1, GRPR | CYP19A1 1525/4885GPR84 1082/4885OPRM1 2150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.