Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24849931 | 0.82 | CYP19A1 (0.35) | GPR84SMPD1CYP19A1 | |
| SCHEMBL24136120 | 0.81 | CPB2 (0.33) | — | |
| SCHEMBL21152292 | 0.80 | CYP19A1 (0.35) | GPR84CYP19A1 | |
| SCHEMBL21557588 | 0.75 | — | — | |
| SCHEMBL22490221 | 0.73 | CYP19A1 (0.40) | GPR84LMNASMN1; SMN2CYP19A1 | |
| SCHEMBL21214497 | 0.71 | OPRM1 (0.32) | — | |
| SCHEMBL25141975 | 0.71 | — | — | |
| SCHEMBL24704471 | 0.70 | — | — | |
| SCHEMBL20273118 | 0.70 | NPC1 (0.35) | GPR84LMNASMN1; SMN2 | |
| SCHEMBL23265136 | 0.69 | SMPD1 (0.48) | SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262070-A1 | Pharmaceutically Active Tetrahydro-Pyrrolizinone Compounds | BAUMANN KARL | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262070-A1 | Pharmaceutically Active Tetrahydro-Pyrrolizinone Compounds | VCAM1, ICAM1, EPCAM | GPR84 508/4885SMPD1 1910/4885SLC9A1 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.