Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.45 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765596 | 1.00 | FOLH1 (0.45) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL25453237 | 1.00 | FOLH1 (0.45) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL22479743 | 0.86 | FOLH1 (0.44) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL7602617 | 0.86 | FOLH1 (0.44) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL21152873 | 0.86 | FOLH1 (0.44) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL13707913 | 0.86 | GABRP (0.48) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL4623229 | 0.86 | GABRP (0.48) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL10093782 | 0.85 | ALDH1A1 (0.38) | FOLH1NAALAD2 | |
| SCHEMBL909914 | 0.85 | FOLH1 (0.57) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL910369 | 0.85 | FOLH1 (0.57) | FOLH1NAALAD2RIMKLAGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023160982-A1 | DOSAGE REGIMEN | ADC THERAPEUTICS SA (CH) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023156434-A1 | COMBINATION THERAPIES FOR TREATMENT OF CANCER COMPRISING B7-H4 ANTIBODY DRUG CONJUGATE | MEDIMMUNE LIMITED (GB) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023088966-A1 | ANTI-PSMA CONJUGATES | ADC THERAPEUTICS SA (CH) | 2023-05-25 | — | — | WO | disclosed |
| US-20190209702-A1 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209702-A1 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | SERPINA6, NR3C1, NR3C2 | FOLH1 895/4885NAALAD2 1893/4885RIMKLA 3690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.