Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13707766 | 1.00 | MMP13 (0.38) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL21134739 | 1.00 | MMP13 (0.38) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL15845208 | 0.90 | MMP13 (0.38) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL15845207 | 0.90 | MMP13 (0.38) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL23845804 | 0.85 | MMP13 (0.36) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL27915723 | 0.85 | CTSS (0.40) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL11100837 | 0.85 | CTSS (0.40) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL8371917 | 0.85 | CTSS (0.40) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL16289346 | 0.84 | MMP13 (0.35) | MMP13AAK1HDAC6HDAC1HDAC2 | |
| SCHEMBL15083200 | 0.84 | MMP13 (0.35) | MMP13AAK1HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508476-B1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | SHANGHAI KECHOW PHARMA INC (CN) | 2023-11-22 | — | — | EP | disclosed |
| EP-3508476-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) | 2019-07-10 | — | — | EP | disclosed |