Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21153269 | 1.00 | MMP13 (0.38) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL13707766 | 1.00 | MMP13 (0.38) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL15845208 | 0.90 | MMP13 (0.38) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL15845207 | 0.90 | MMP13 (0.38) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL23845804 | 0.85 | MMP13 (0.36) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL27915723 | 0.85 | CTSS (0.40) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL11100837 | 0.85 | CTSS (0.40) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL8371917 | 0.85 | CTSS (0.40) | MMP13AAK1MEN1GAAKMT2A | |
| SCHEMBL16289346 | 0.84 | MMP13 (0.35) | MMP13AAK1HDAC6HDAC1HDAC2 | |
| SCHEMBL15083200 | 0.84 | MMP13 (0.35) | MMP13AAK1HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008286-B2 | Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation | SHANGHAI KECHOW PHARMA, INC (CN) | 2021-05-18 | — | — | US | disclosed |
| US-20190202779-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | SHANGHAI KECHOW PHARMA, INC. (CN) | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190202779-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | MGMT, PRMT8, SULT1A1 | MMP13 4681/4885AAK1 4149/4885MEN1 330/4885 |
| US-11008286-B2 | Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation | MGMT, GSTA1, PRMT1 | MMP13 4276/4885AAK1 2409/4885MEN1 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.