Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23385986 | 0.92 | MEN1 (0.46) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL18410331 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10FAAHGAA | |
| SCHEMBL16485547 | 0.79 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10FAAHGAA | |
| SCHEMBL23718715 | 0.79 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10FAAHGAA | |
| SCHEMBL17574393 | 0.76 | MEN1 (0.48) | MEN1KMT2AALDH1A1LMNAPSMB5 | |
| SCHEMBL23289286 | 0.76 | MEN1 (0.48) | MEN1KMT2AALDH1A1LMNAPSMB5 | |
| SCHEMBL27743922 | 0.75 | CASP2 (0.45) | ALDH1A1LMNAHSD17B10FAAHGAA | |
| SCHEMBL21570070 | 0.74 | LMNA (0.38) | ALDH1A1LMNAHSD17B10FAAH | |
| SCHEMBL25415706 | 0.74 | TDP1 (0.41) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL24909274 | 0.74 | MEN1 (0.46) | MEN1KMT2AALDH1A1GAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136487-A2 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |