Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TYMS | P04818 | 7/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291732 | 0.84 | TYMS (0.53) | KMT2AMEN1POLBTYMSBCL2 | |
| SCHEMBL18071160 | 0.82 | BCL2 (0.56) | KMT2AMEN1POLBTYMSBCL2 | |
| SCHEMBL30557400 | 0.79 | TYMS (0.47) | KMT2AMEN1POLBTYMSUSP2 | |
| SCHEMBL16684611 | 0.79 | TYMS (0.47) | KMT2AMEN1POLBTYMSUSP2 | |
| SCHEMBL18105551 | 0.76 | TYMS (0.44) | KMT2AMEN1POLBTYMSBCL2 | |
| SCHEMBL19929266 | 0.76 | TYMS (0.44) | KMT2AMEN1POLBTYMSBCL2 | |
| SCHEMBL30933051 | 0.75 | ALDH1A1 (0.59) | KMT2AMEN1POLBTYMSMAPT | |
| SCHEMBL16684654 | 0.75 | ALDH1A1 (0.59) | KMT2AMEN1POLBTYMSMAPT | |
| SCHEMBL30761754 | 0.75 | KMT2A (0.76) | KMT2AMEN1POLBTYMSUSP2 | |
| SCHEMBL6548245 | 0.75 | KMT2A (0.76) | KMT2AMEN1POLBTYMSUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274334-B1 | CYANATED BENZOXANTHENE AND BENZOTHIOXANTHENE COMPOUNDS | BASF SE (DE) | 2019-07-10 | — | — | EP | disclosed |