Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291732 | 0.88 | TYMS (0.53) | BCL2MCL1POLBKMT2AMEN1 | |
| SCHEMBL16684611 | 0.82 | TYMS (0.47) | BCL2MCL1POLBKMT2AMEN1 | |
| SCHEMBL30557400 | 0.82 | TYMS (0.47) | BCL2MCL1POLBKMT2AMEN1 | |
| SCHEMBL21154252 | 0.82 | KMT2A (0.46) | BCL2MCL1POLBKMT2AMEN1 | |
| SCHEMBL23430836 | 0.79 | MCL1 (0.56) | BCL2MCL1POLBKMT2AMEN1 | |
| SCHEMBL19929266 | 0.79 | TYMS (0.44) | BCL2MCL1POLBKMT2AMEN1 | |
| SCHEMBL18105551 | 0.79 | TYMS (0.44) | BCL2MCL1POLBKMT2AMEN1 | |
| SCHEMBL30933051 | 0.78 | ALDH1A1 (0.59) | POLBKMT2AMEN1TYMSLMNA | |
| SCHEMBL16684654 | 0.78 | ALDH1A1 (0.59) | POLBKMT2AMEN1TYMSLMNA | |
| SCHEMBL6548245 | 0.78 | KMT2A (0.76) | MCL1POLBKMT2AMEN1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676998-B2 | Class of green/yellow emitting phosphors based on derivatives of benzimidazoxanthenoisoquinolinone for LED lighting | PHILIPS LIGHTING HOLDING B.V. (NL) | 2017-06-13 | — | — | US | disclosed |
| US-20160264860-A1 | CLASS OF GREEN/YELLOW EMITTING PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING | SIGNIFY HOLDING B.V. (NL) | 2016-09-15 | — | — | US | disclosed |