Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | JUN | P05412 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | IKBKB | O14920 | 2/20 | 0.53 |
| ▸ | CHUK | O15111 | 2/20 | 0.53 |
| ▸ | IKBKG | Q9Y6K9 | 2/20 | 0.53 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9972294 | 0.93 | SMN1; SMN2 (0.69) | SMN1; SMN2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL16621565 | 0.88 | CYP1A2 (0.63) | SMN1; SMN2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL15298981 | 0.87 | TNFRSF1A (0.64) | SMN1; SMN2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL18470971 | 0.85 | GLO1 (0.63) | SMN1; SMN2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL18699339 | 0.84 | JUN (0.71) | SMN1; SMN2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL11928836 | 0.83 | KDM4E (0.50) | SMN1; SMN2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL9972319 | 0.83 | KDM4E (0.56) | SMN1; SMN2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL15298299 | 0.83 | KDM4E (0.56) | SMN1; SMN2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL16621556 | 0.81 | JUN (0.80) | SMN1; SMN2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL5218481 | 0.80 | ALDH1A1 (0.76) | SMN1; SMN2KDM4EALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508855-A1 | METHOD FOR THE SELECTION OF PATIENTS AND KIT | Allianz Pharmascience Ltd (TW) | 2019-07-10 | — | — | EP | disclosed |