Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 4/20 | 0.39 |
| ▸ | GSTM2 | P28161 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974127 | 0.85 | TXNRD1 (0.46) | ALDH1A1HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL21155893 | 0.84 | MGAM (0.41) | ALDH1A1HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL21155899 | 0.81 | MEN1 (0.50) | ALDH1A1MEN1KMT2ATDP1GAA | |
| SCHEMBL21155437 | 0.80 | MAPT (0.44) | ALDH1A1ALOX12CYP2C19MEN1KMT2A | |
| SCHEMBL22665548 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10GAAIDO1 | |
| SCHEMBL21155818 | 0.77 | GSTP1 (0.45) | ALDH1A1CYP2D6CYP2C9HPGDALOX15 | |
| SCHEMBL21155164 | 0.75 | POLB (0.41) | ALDH1A1HPGDALOX12MEN1KMT2A | |
| SCHEMBL16919574 | 0.75 | TDP1 (0.42) | ALDH1A1CYP2D6CYP2C9CYP2C19HIF1A | |
| SCHEMBL21155892 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ATDP1GAA | |
| SCHEMBL10452725 | 0.73 | ALDH1A1 (0.55) | ALDH1A1CYP2D6CYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512848-B1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-11-18 | — | — | EP | disclosed |
| US-20190214574-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190214574-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | CYCS, CYP3A4, CYP2E1 | ALDH1A1 506/4885CYP2D6 82/4885CYP2C9 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.