Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 10/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TDO2 | P48775 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21155177 | 0.86 | POLB (0.43) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL16231228 | 0.85 | ALDH1A1 (0.44) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL21114912 | 0.82 | TXNRD1 (0.42) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL21155172 | 0.81 | KMT2A (0.43) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL21155838 | 0.81 | ALDH1A1 (0.38) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL21155159 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL21155439 | 0.79 | MAPT (0.38) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL19051828 | 0.78 | MAPT (0.71) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL21155840 | 0.78 | MEN1 (0.46) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL18416509 | 0.77 | ALDH1A1 (0.45) | MAPTALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190214574-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190214574-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | CYCS, CYP3A4, CYP2E1 | MAPT 2010/4885ALDH1A1 506/4885L3MBTL1 4160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.