Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.34 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21113204 | 0.92 | RAB9A (0.42) | ALDH1A1LMNASMN1; SMN2POLBFKBP1A | |
| SCHEMBL21113144 | 0.91 | RAB9A (0.42) | ALDH1A1SMN1; SMN2L3MBTL1RAB9AKDM4E | |
| SCHEMBL21157287 | 0.89 | TSHR (0.41) | SMN1; SMN2EZH2EEDRBBP4SUZ12 | |
| SCHEMBL21157283 | 0.87 | ALOX15 (0.41) | ALDH1A1LMNASMN1; SMN2POLBRAB9A | |
| SCHEMBL19964426 | 0.87 | NPC1 (0.41) | ALDH1A1LMNASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL21157293 | 0.86 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2EZH2EED | |
| SCHEMBL21156593 | 0.86 | EZH2 (0.38) | ALDH1A1LMNASMN1; SMN2EZH2EED | |
| SCHEMBL21157346 | 0.86 | EZH2 (0.44) | ALDH1A1LMNASMN1; SMN2EZH2EED | |
| SCHEMBL21157370 | 0.86 | EZH2 (0.48) | ALDH1A1LMNASMN1; SMN2EZH2EED | |
| SCHEMBL21157291 | 0.85 | EED (0.43) | ALDH1A1LMNASMN1; SMN2EZH2EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968215-B2 | Pyrido five-element aromatic ring compound, preparation method therefor and use thereof | SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. (CN) | 2021-04-06 | — | — | US | disclosed |
| US-20190211010-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | HAIHE BIOPHARMA CO. LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968215-B2 | Pyrido five-element aromatic ring compound, preparation method therefor and use thereof | EZH2, IKZF2, SUZ12 | ALDH1A1 2816/4885LMNA 2826/4885SMN1; SMN2 4308/4885 |
| US-20190211010-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | EZH2, IKZF2, SUZ12 | ALDH1A1 2816/4885LMNA 2826/4885SMN1; SMN2 4308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.