Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21156962 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HPGDLMNAGLASMN1; SMN2 | |
| SCHEMBL20344487 | 0.82 | ADH1B (0.52) | ALDH1A1HPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL22048707 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HPGDLMNAGLASMN1; SMN2 | |
| SCHEMBL20393584 | 0.80 | ALDH1A1 (0.42) | ALDH1A1HPGDLMNAGLASMN1; SMN2 | |
| SCHEMBL5528831 | 0.72 | CYP2C9 (0.66) | ALDH1A1HPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL7449229 | 0.71 | ADH1B (0.52) | ALDH1A1HPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL31566 | 0.71 | ADH1B (0.61) | ALDH1A1HPGDLMNAGLASMN1; SMN2 | |
| SCHEMBL28944284 | 0.71 | ALDH1A1 (0.45) | ALDH1A1HPGDLMNAGLASMN1; SMN2 | |
| SCHEMBL19980227 | 0.71 | ALDH1A1 (0.45) | ALDH1A1HPGDLMNAGLASMN1; SMN2 | |
| SCHEMBL15905318 | 0.70 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNAGLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508484-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-07-10 | — | — | EP | disclosed |