SCHEMBL21157154

SCHEMBL21157154

c1ccc(-c2cc(-c3ccccc3)cc(-c3ccccc3-c3ccccc3-c3cccc4c3sc3c(-c5ccccc5-c5ccccc5-c5cc(-c6ccccc6)cc(-c6ccccc6)c5)cc5ccccc5c34)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
HPGD P15428 3/20 0.42
TSHR P16473 3/20 0.42
MAPK1 P28482 3/20 0.42
HSD17B10 Q99714 3/20 0.42
CASP1 P29466 2/20 0.42
HIF1A Q16665 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
LIMK1 P53667 1/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
KDM4E B2RXH2 3/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 1/20 0.34
MPI P34949 1/20 0.34
GPR84 Q9NQS5 2/20 0.33
CDK4 P11802 1/20 0.33
CCND1 P24385 1/20 0.33
PTGES O14684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21157894 1.00 ALDH1A1 (0.42) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL21157895 0.88 ALDH1A1 (0.35) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL21157149 0.88 ALDH1A1 (0.35) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL21157800 0.87 ALDH1A1 (0.40) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL21157889 0.85 GPR84 (0.34) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL21157150 0.85 GPR84 (0.34) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL21157899 0.85 LIMK1 (0.42) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL21156611 0.85 LIMK1 (0.42) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL21157891 0.83 ALDH1A1 (0.41) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL21157805 0.83 ALDH1A1 (0.41) ALDH1A1HPGDTSHRMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190214577-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214577-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE TEAD2, TEAD3, TEAD1 ALDH1A1 1545/4885HPGD 3226/4885TSHR 3560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.