Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21157920 | 1.00 | HSD17B10 (0.39) | HSD17B10ALKBH5FTOHPGDBRD4 | |
| SCHEMBL21156638 | 0.88 | HSD17B10 (0.44) | HSD17B10ALKBH5FTOHPGDBRD4 | |
| SCHEMBL21157926 | 0.88 | HSD17B10 (0.40) | HSD17B10ALKBH5FTOHPGDBRD4 | |
| SCHEMBL21157188 | 0.85 | L3MBTL1 (0.35) | HSD17B10HPGDHSD11B1COMTMAPT | |
| SCHEMBL26242847 | 0.81 | HSD17B10 (0.41) | HSD17B10ALKBH5FTOHPGDBRD4 | |
| SCHEMBL21156626 | 0.81 | ALDH1A1 (0.38) | KMT2AMEN1NPC1MAPTHTT | |
| SCHEMBL21156628 | 0.81 | ALDH1A1 (0.38) | KMT2AMEN1NPC1MAPTHTT | |
| SCHEMBL14931060 | 0.81 | HSD17B10 (0.46) | HSD17B10ALKBH5FTOHPGDBRD4 | |
| SCHEMBL21156637 | 0.80 | CYP1A2 (0.36) | HSD17B10HPGDMAPTATMSMN1; SMN2 | |
| SCHEMBL21157227 | 0.79 | ALDH1A1 (0.34) | HSD17B10NPC1MAPTXBP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190214577-A1 | THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190214577-A1 | THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE | TEAD2, TEAD3, TEAD1 | HSD17B10 2397/4885ALKBH5 1726/4885FTO 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.