Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201233 | 0.91 | TAAR1 (0.46) | FFAR1FFAR4ESR1NR3C1PGR | |
| SCHEMBL21157262 | 0.79 | TAAR1 (0.54) | TAAR1ALDH1A1RAB9A | |
| SCHEMBL6586 | 0.79 | FFAR1 (0.68) | FFAR1FFAR4ESR1NR3C1PGR | |
| SCHEMBL7332798 | 0.77 | TAAR1 (0.57) | FFAR1FFAR4ESR1NR3C1PGR | |
| SCHEMBL4234560 | 0.74 | ALDH1A1 (0.60) | FFAR1FFAR4ESR1NR3C1PGR | |
| SCHEMBL5666545 | 0.74 | TAAR1 (0.53) | FFAR1FFAR4ESR1NR3C1PGR | |
| SCHEMBL3962652 | 0.74 | TAAR1 (0.53) | FFAR1FFAR4ESR1NR3C1PGR | |
| SCHEMBL2754670 | 0.74 | TAAR1 (0.58) | FFAR1FFAR4ESR1NR3C1PGR | |
| SCHEMBL6378 | 0.73 | TAAR1 (0.53) | FFAR1FFAR4ESR1NR3C1PGR | |
| SCHEMBL4237046 | 0.73 | NPC1 (0.54) | FFAR1FFAR4ESR1NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135604-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |