Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21157247 | 0.91 | FFAR1 (0.50) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL21149844 | 0.83 | HDAC1 (0.58) | FFAR1NPC1HDAC3HDAC1HDAC2 | |
| SCHEMBL21149328 | 0.82 | PLAAT3 (0.47) | TAAR1FFAR1FFAR4NPC1HDAC3 | |
| SCHEMBL1445967 | 0.80 | HDAC3 (0.63) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL4686018 | 0.79 | TAAR1 (0.50) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL22201278 | 0.79 | MAPT (0.58) | FFAR1NPC1HDAC3HDAC1HDAC2 | |
| SCHEMBL22201127 | 0.77 | MAPT (0.61) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL22201222 | 0.77 | CYP1A2 (0.66) | FFAR1HCAR2HDAC3HDAC1HDAC2 | |
| SCHEMBL4686023 | 0.77 | TAAR1 (0.56) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL30828038 | 0.77 | TAAR1 (0.56) | TAAR1FFAR1FFAR4ESR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |