Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 9/20 | 0.43 |
| ▸ | ACACA | Q13085 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16479603 | 0.84 | CYP2D6 (0.58) | MKNK1MKNK2HSD17B1HSD17B2CYP2A6 | |
| SCHEMBL21156450 | 0.82 | RARB (0.51) | RARBCYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL17795420 | 0.82 | CYP2D6 (0.55) | RARBMKNK1MKNK2HSD17B1HSD17B2 | |
| SCHEMBL21156921 | 0.81 | NAAA (0.45) | MKNK1MKNK2HSD17B1HSD17B2CYP2A6 | |
| SCHEMBL13526846 | 0.81 | MKNK1 (0.47) | MKNK1MKNK2HSD17B1HSD17B2CYP2A6 | |
| SCHEMBL1422493 | 0.77 | MKNK1 (0.59) | MKNK1MKNK2HSD17B1HSD17B2CYP2A6 | |
| SCHEMBL13251236 | 0.77 | TDP1 (0.55) | RARBTDP1 | |
| SCHEMBL21157729 | 0.77 | RARB (0.52) | RARBCYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL21156862 | 0.77 | CYP19A1 (0.73) | RARBMKNK1MKNK2CYP2A6CYP3A4 | |
| SCHEMBL13251245 | 0.76 | RARB (0.62) | RARBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190211046-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190211046-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PROKR1, ARG1, ARG2 | RARB 3457/4885MKNK1 2558/4885MKNK2 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.