Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 7/20 | 0.36 |
| ▸ | CA2 | P00918 | 7/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29436967 | 0.89 | STING1 (0.39) | SERPINE1STING1CA1CA2HDAC1 | |
| SCHEMBL21643816 | 0.89 | STING1 (0.39) | SERPINE1STING1CA1CA2HDAC1 | |
| SCHEMBL20889072 | 0.87 | STING1 (0.45) | STING1 | |
| SCHEMBL29406354 | 0.87 | STING1 (0.45) | STING1 | |
| SCHEMBL29012734 | 0.87 | STING1 (0.45) | STING1 | |
| SCHEMBL22121412 | 0.82 | STING1 (0.38) | STING1CA1CA2HDAC1BRD4 | |
| SCHEMBL23077453 | 0.81 | STING1 (0.40) | STING1CA1CA2HDAC1BRD4 | |
| SCHEMBL21158189 | 0.81 | STING1 (0.37) | STING1AAK1 | |
| SCHEMBL29403353 | 0.81 | GAA (0.41) | STING1HDAC1BRD4AAK1PRSS1 | |
| SCHEMBL28416129 | 0.81 | GAA (0.41) | STING1HDAC1BRD4AAK1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019134705-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2019-07-11 | — | — | WO | disclosed |