Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23861741 | 0.82 | TSHR (0.46) | SMN1; SMN2TSHRALDH1A1HRH3SLC29A1 | |
| SCHEMBL25623837 | 0.82 | TSHR (0.46) | SMN1; SMN2TSHRALDH1A1CYP2D6MEN1 | |
| SCHEMBL28362252 | 0.80 | HRH3 (0.38) | TSHRALDH1A1HRH3CYP2D6MEN1 | |
| SCHEMBL15512770 | 0.78 | KDM4E (0.39) | ALDH1A1HRH3SLC29A1CYP2D6MEN1 | |
| SCHEMBL15499958 | 0.78 | KDM4E (0.39) | ALDH1A1HRH3SLC29A1CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL15512407 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HRH3SLC29A1CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL15512408 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HRH3SLC29A1CYP2D6MEN1 | |
| SCHEMBL1474423 | 0.75 | TACR1 (0.40) | KDM1ATSHRALDH1A1HRH3CYP2D6 | |
| SCHEMBL81690 | 0.73 | HRH3 (0.41) | KDM1AALDH1A1HRH3MEN1KMT2A | |
| SCHEMBL11593239 | 0.73 | SIGMAR1 (0.50) | SMN1; SMN2TSHRALDH1A1HRH3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190201367-A1 | PRODRUGS OF FUMARATES AND THEIR USE IN TREATING VARIOUS DISEASES | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190201367-A1 | PRODRUGS OF FUMARATES AND THEIR USE IN TREATING VARIOUS DISEASES | FH, FAH, GLS2 | SMN1; SMN2 1861/4885KDM1A 1659/4885TSHR 4379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.