Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177971 | 0.86 | CYP1A2 (0.41) | ALDH1A1LMNANPC1RAB9AKDM4E | |
| SCHEMBL24562966 | 0.84 | NPC1 (0.39) | ALDH1A1LMNANPC1RAB9ARXFP1 | |
| SCHEMBL14125957 | 0.81 | FBP1 (0.45) | ALDH1A1LMNANPC1RAB9ARXFP1 | |
| SCHEMBL21158774 | 0.79 | SMN1; SMN2 (0.37) | ALDH1A1LMNANPC1RAB9AHSD17B10 | |
| SCHEMBL7140031 | 0.79 | TARBP2 (0.44) | ALDH1A1LMNANPC1RAB9AHSD17B10 | |
| SCHEMBL5013490 | 0.78 | STING1 (0.36) | ALDH1A1LMNANPC1RAB9AHSD17B10 | |
| SCHEMBL408193 | 0.77 | ALDH1A1 (0.53) | ALDH1A1LMNANPC1RAB9ANPSR1 | |
| SCHEMBL3826654 | 0.77 | RNASEH1 (0.46) | ALDH1A1LMNANPSR1HSD17B10KDM4E | |
| SCHEMBL29689460 | 0.76 | SMN1; SMN2 (0.31) | ALDH1A1LMNANPC1RAB9AHSD17B10 | |
| Hydrochloric Acid SCHEMBL30823039 | 0.76 | STING1 (0.35) | ALDH1A1LMNANPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471056-B | Macrocyclic immunomodulator | 成都先导药物开发股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-110016021-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111471056-A | Macrocyclic immunomodulator | 成都先导药物开发股份有限公司 | 2020-07-31 | — | — | CN | disclosed |
| WO-2020151682-A1 | MACROCYCLIC IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2020-07-30 | — | — | WO | disclosed |
| WO-2019134707-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2019-07-11 | — | — | WO | disclosed |