Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13741585 | 0.75 | NFKB1 (0.32) | ODC1KDM4ELMNAMAPTRAB9A | |
| SCHEMBL7639242 | 0.73 | ALDH1A1 (0.32) | ODC1 | |
| SCHEMBL714289 | 0.71 | ODC1 (0.33) | ODC1KDM4ELMNAMAPTRAB9A | |
| SCHEMBL9187883 | 0.70 | — | — | |
| SCHEMBL26977044 | 0.69 | NFKB1 (0.37) | LMNABLM | |
| SCHEMBL19492027 | 0.67 | TSHR (0.32) | TDP1 | |
| SCHEMBL18920432 | 0.67 | DNM1 (0.40) | CHRM2LMNABLM | |
| SCHEMBL1262998 | 0.67 | DNM1 (0.40) | CHRM2LMNABLM | |
| SCHEMBL2601753 | 0.65 | CHRM2 (0.36) | TDP1CHRM2LMNABLM | |
| SCHEMBL8754089 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312179-B1 | FUSED-RING OR TRICYCLIC ARYL PYRIMIDINE COMPOUND USED AS KINASE INHIBITOR | NANJING SANHOME PHARMACEUTICAL CO LTD (CN) | 2019-07-10 | — | — | EP | disclosed |