Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 10/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21899550 | 0.78 | BTK (0.44) | KAT2BLRRK2BPTFBTKNLRP3 | |
| SCHEMBL27782780 | 0.73 | HPGDS (0.69) | BTKHPGDSJAK3 | |
| SCHEMBL3513711 | 0.73 | KAT2B (0.44) | KAT2BLRRK2BPTFNLRP3CHEK1 | |
| SCHEMBL25060362 | 0.70 | BTK (0.59) | KAT2BLRRK2BTKNLRP3CHEK1 | |
| SCHEMBL17622721 | 0.70 | KAT2B (0.45) | KAT2BLRRK2BPTFNLRP3ADORA1 | |
| SCHEMBL19649120 | 0.69 | BTK (0.61) | KAT2BBTK | |
| SCHEMBL21705081 | 0.68 | LRRK2 (0.54) | LRRK2JAK3 | |
| SCHEMBL30973591 | 0.68 | KAT2B (0.47) | KAT2BBPTFNLRP3IL1B | |
| SCHEMBL13226128 | 0.67 | ROCK2 (0.52) | KAT2BNLRP3CHEK1 | |
| SCHEMBL12676513 | 0.66 | POLB (0.49) | KAT2BBPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |