Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21234766 | 0.91 | CYP2A6 (0.39) | CYP2A6ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL21160425 | 0.90 | CYP2A6 (0.38) | CYP2A6TDP1ALDH1A1TSHRLMNA | |
| SCHEMBL21036814 | 0.86 | CYP2A6 (0.44) | CYP2A6ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL21234933 | 0.78 | ALDH1A1 (0.32) | TDP1ALDH1A1TSHRKMT2AMAPT | |
| SCHEMBL21234765 | 0.77 | CYP2A6 (0.40) | CYP2A6 | |
| SCHEMBL21234686 | 0.76 | CYP2A6 (0.53) | CYP2A6TDP1ALDH1A1KMT2AMAPT | |
| SCHEMBL25003651 | 0.74 | — | — | |
| SCHEMBL24991952 | 0.74 | CISD1 (0.42) | ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL24992673 | 0.73 | — | — | |
| SCHEMBL24991969 | 0.72 | CYP2A6 (0.36) | CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011658-A1 | METHOD FOR DETECTING AND QUANTIFYING RNA | 纳莹(上海)生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |
| WO-2023011657-A1 | METHOD FOR DETECTING AND QUANTIFYING RNA | 纳莹(上海)生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |
| US-11365203-B2 | Fluorescent dye and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD. (CN) | 2022-06-21 | — | — | US | disclosed |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-08-06 | — | — | US | disclosed |
| US-20190241584-A1 | FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-08-08 | — | — | US | disclosed |
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | HNRNPF, HNRNPUL2, RAB5IF | CYP2A6 4407/4885TDP1 2012/4885ALDH1A1 3152/4885 |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | WASF2, FAM162A, HASPIN | CYP2A6 4362/4885TDP1 2196/4885ALDH1A1 3475/4885 |
| US-20190241584-A1 | FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF | DNASE1, POLRMT, DCLRE1B | CYP2A6 2814/4885TDP1 137/4885ALDH1A1 422/4885 |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | HNRNPF, HNRNPUL2, RAB5IF | CYP2A6 4407/4885TDP1 2012/4885ALDH1A1 3152/4885 |
| US-11365203-B2 | Fluorescent dye and preparation method and use thereof | DNASE1, POLRMT, DCLRE1B | CYP2A6 2814/4885TDP1 137/4885ALDH1A1 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.