Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23764904 | 0.86 | NUDT1 (0.52) | SMN1; SMN2NUDT1ALDH1A1RAB9AMEN1 | |
| SCHEMBL23481321 | 0.84 | CA1 (0.45) | SMN1; SMN2NUDT1ALDH1A1RAB9AMEN1 | |
| SCHEMBL18573848 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2NUDT1ALDH1A1RAB9AMEN1 | |
| SCHEMBL24755030 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2NUDT1ALDH1A1RAB9AMEN1 | |
| SCHEMBL24895914 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2NUDT1ALDH1A1RAB9AMEN1 | |
| SCHEMBL15483629 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2NUDT1ALDH1A1RAB9AMEN1 | |
| SCHEMBL31141585 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2NUDT1ALDH1A1RAB9AMEN1 | |
| SCHEMBL2749327 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2NUDT1ALDH1A1RAB9AMEN1 | |
| SCHEMBL18573951 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2NUDT1ALDH1A1RAB9AMEN1 | |
| SCHEMBL20434695 | 0.79 | ERCC1 (0.44) | SMN1; SMN2NUDT1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20210382060-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | Shanghai Glory Capital Management Ltd. (CN) | 2021-12-09 | — | — | US | disclosed |
| US-20210085805-A1 | FLUOROPHORES FOR SUPER-RESOLUTION IMAGING | HOWARD HUGHES MEDICAL INSTITUTE | 2021-03-25 | — | — | US | disclosed |
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | HNRNPF, HNRNPUL2, RAB5IF | SMN1; SMN2 1496/4885NUDT1 785/4885ALDH1A1 3152/4885 |
| US-20210085805-A1 | FLUOROPHORES FOR SUPER-RESOLUTION IMAGING | CHAT, FABP7, CD68 | SMN1; SMN2 778/4885NUDT1 2010/4885ALDH1A1 845/4885 |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | HNRNPF, HNRNPUL2, RAB5IF | SMN1; SMN2 1496/4885NUDT1 785/4885ALDH1A1 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.