Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 3/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 2/20 | 0.44 |
| ▸ | LSS | P48449 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD1 | P21728 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | DRD5 | P21918 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28286896 | 0.92 | GNAO1 (0.57) | GNAO1GNAI3GNAI1BCHEKCNH2 | |
| Hydrochloric Acid SCHEMBL11479318 | 0.89 | GNAO1 (0.63) | GNAO1GNAI3GNAI1KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL11489213 | 0.89 | GNAO1 (0.63) | GNAO1GNAI3GNAI1KCNH2DRD2 | |
| SCHEMBL9344937 | 0.89 | GNAO1 (0.50) | GNAO1GNAI3GNAI1BCHEKCNH2 | |
| Fluoride SCHEMBL30330478 | 0.87 | GNAO1 (0.55) | GNAO1GNAI3GNAI1BCHEKCNH2 | |
| Hydrochloric Acid SCHEMBL30330729 | 0.87 | GNAO1 (0.59) | GNAO1GNAI3GNAI1BCHEKCNH2 | |
| Fluoride SCHEMBL30330799 | 0.87 | GNAO1 (0.55) | GNAO1GNAI3GNAI1BCHEKCNH2 | |
| Hydrochloric Acid SCHEMBL30330775 | 0.87 | GNAO1 (0.59) | GNAO1GNAI3GNAI1BCHEKCNH2 | |
| Hydrochloric Acid SCHEMBL30330682 | 0.87 | GNAO1 (0.59) | GNAO1GNAI3GNAI1BCHEKCNH2 | |
| Fluoride SCHEMBL30330330 | 0.87 | GNAO1 (0.55) | GNAO1GNAI3GNAI1BCHEKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380588-A1 | Novel Compounds and Uses Thereof | OXFORD FINANCE LLC | 2021-12-09 | — | — | US | disclosed |
| US-10329280-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380588-A1 | Novel Compounds and Uses Thereof | RB1, VEGFA, UACA | GNAO1 1817/4885GNAI3 552/4885GNAI1 530/4885 |
| US-10329280-B2 | Urea derivatives and uses thereof | UACA, RB1, FLT1 | GNAO1 2556/4885GNAI3 949/4885GNAI1 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.