SCHEMBL2116127

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20465813	0.79	NOS3 (0.52)	LMNANOS3NOS2NOS1GABRP
	SCHEMBL2610401	0.79	LMNA (0.41)	LMNAKDM4EPRKCEALDH1A1MYLK
	SCHEMBL20465808	0.78	LMNA (0.43)	LMNANOS3NOS2NOS1GABRP
	SCHEMBL14288612	0.78	CYP3A4 (0.40)	LMNAGABRPGABRDGABRA1GABRB1
	SCHEMBL20489645	0.78	LMNA (0.36)	LMNAPRKCEALDH1A1MYLKMEN1
	SCHEMBL30935487	0.76	GABRP (0.36)	NOS3NOS2NOS1GABRPGABRD
	SCHEMBL20489515	0.71	LMNA (0.45)	LMNANOS3NOS2NOS1GABRP
	SCHEMBL24921036	0.71	LMNA (0.32)	LMNAKDM4EPRKCEALDH1A1MYLK
	SCHEMBL2117006	0.71	ALOX5AP (0.42)	NOS3NOS2NOS1ALDH1A1MEN1
	SCHEMBL2123145	0.70	LMNA (0.47)	LMNANOS3NOS2NOS1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.