Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337970 | 0.94 | SMN1; SMN2 (0.70) | HSD17B3HPGDSMN1; SMN2L3MBTL1GSK3B | |
| SCHEMBL9337930 | 0.89 | HSD17B3 (0.55) | HSD17B3HPGDSMN1; SMN2L3MBTL1GSK3B | |
| SCHEMBL26254861 | 0.89 | HSD17B3 (0.82) | HSD17B3HPGDSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL1091479 | 0.88 | HSD17B3 (0.69) | HSD17B3L3MBTL1GSK3BHDAC1HDAC8 | |
| SCHEMBL241664 | 0.86 | GSK3B (0.70) | SMN1; SMN2GSK3BHDAC1HDAC8HDAC3 | |
| SCHEMBL4198536 | 0.86 | HSD17B3 (0.70) | HSD17B3GSK3BHDAC1HDAC8HDAC3 | |
| SCHEMBL7907717 | 0.84 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL7789360 | 0.84 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL7789291 | 0.84 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL4293741 | 0.84 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037509-A | Process for producing 1-bromo-4-phenylbutane | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-03-14 | — | — | US | claimed |
| JP-10087643-A | — | — | None | — | — | JP | disclosed |
| JP-11292808-A | — | — | None | — | — | JP | disclosed |
| EP-4371982-A2 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| US-20240115711-A1 | Novel Bifunctional Molecules For Targeted Protein Degradation | AMPHISTA THERAPEUTICS LIMITED (GB) | 2024-04-11 | — | — | US | disclosed |
| EP-3583096-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2024-03-27 | — | — | EP | disclosed |
| CN-117660019-A | Liquid crystal compound with high birefringence, synthesis method, liquid crystal composition and application | 西安近代化学研究所 | 2024-03-08 | — | — | CN | disclosed |
| EP-4263511-A1 | NOVEL BIFUNCTIONAL MOLECULES FOR TARGETED PROTEIN DEGRADATION | Amphista Therapeutics Ltd (GB) | 2023-10-25 | — | — | EP | disclosed |
| CN-116897150-A | Novel bifunctional molecules for protein-targeted degradation | 安菲斯塔治疗有限公司 | 2023-10-17 | — | — | CN | disclosed |
| WO-2023142460-A1 | METHOD FOR SYNTHESIZING ARYL PHENOL BY MEANS OF REACTION BETWEEN ARYL HALIDE AND PHENOL COMPOUND UNDER INDUCTION OF VISIBLE LIGHT | 苏州大学 | 2023-08-03 | — | — | WO | disclosed |
| US-4820800-A | Arylene sulfide polymers | PHILLIPS PETROLEUM COMPANY (US) | 1989-04-11 | — | — | US | disclosed |
| US-4293552-A | Novel 1-(mono-o-substituted benzoyl)-3-(substituted pyrazinyl) ureas | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-RE30563-E | Preparation of benzoylureas | ELI LILLY AND COMPANY (US) | 1981-03-31 | — | — | US | disclosed |
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4133956-A | Preparation of benzoylureas | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-4069377-A | Polymerization of ethylenically unsaturated monomers employing secondary-aliphatic α-substituted azoalkanes | PENNWALT CORPORATION | 1978-01-17 | — | — | US | disclosed |
| US-4028344-A | FOAMING AGENTS, FREE RADICAL INITIATORS | PENNWALT CORPORATION (US) | 1977-06-07 | — | — | US | disclosed |
| US-4025502-A | POLYMERIZATION CATALYSTS, CURING AGENTS | PENNWALT CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-4009157-A | POLYESTER FOAMING AGENTS, FREE RADICAL CATALYSTS | PENNWALT CORPORATION (US) | 1977-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240115711-A1 | Novel Bifunctional Molecules For Targeted Protein Degradation | PSMG3, MYCBP2, PSME2 | HSD17B3 4433/4885HPGD 3461/4885SMN1; SMN2 2781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.