Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATG7 | O95352 | 9/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16450527 | 0.84 | TK1 (0.34) | TYMSPOLB | |
| SCHEMBL21414072 | 0.83 | TK1 (0.44) | — | |
| SCHEMBL25514132 | 0.83 | TK1 (0.44) | — | |
| SCHEMBL25513903 | 0.79 | ALDH1A1 (0.41) | TYMSPOLB | |
| SCHEMBL24730191 | 0.78 | POLB (0.49) | TYMSPOLB | |
| SCHEMBL25141915 | 0.76 | TYMP (0.36) | TYMS | |
| SCHEMBL25757703 | 0.75 | TYMS (0.36) | TYMSPOLB | |
| SCHEMBL21163947 | 0.74 | POLB (0.63) | TYMSPOLB | |
| SCHEMBL20109714 | 0.74 | POLB (0.63) | TYMSPOLB | |
| SCHEMBL20115166 | 0.74 | POLB (0.63) | TYMSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298023-B1 | NUCLEOSIDE-LIPID COMPOUNDS WITH PH-SENSITIVE DIALKYLORTHOESTER CHAINS AND THEIR USE FOR TRANSPORTATION OR VECTORIZATION OF AT LEAST ONE THERAPEUTIC AGENT | UNIV BORDEAUX (FR) | 2019-07-10 | — | — | EP | disclosed |