Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TK2 | O00142 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21414072 | 1.00 | TK1 (0.44) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL16450527 | 0.89 | TK1 (0.34) | TK1LMNASMN1; SMN2TK2 | |
| SCHEMBL22143535 | 0.85 | TK1 (0.50) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL19033288 | 0.85 | TK1 (0.50) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL21163946 | 0.83 | TYMS (0.37) | — | |
| SCHEMBL21378148 | 0.82 | LMNA (0.58) | TK1LMNATSHRBLMPMP22 | |
| SCHEMBL25838268 | 0.81 | LMNA (0.50) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL21778177 | 0.80 | KDM4E (0.43) | TK1LMNATK2TSHRBLM | |
| SCHEMBL22315079 | 0.80 | RNASE1 (0.35) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL25757703 | 0.79 | TYMS (0.36) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |