Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 4/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742872 | 0.91 | ALOX5 (0.49) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL15682270 | 0.88 | ALOX5 (0.46) | ALOX5GGPS1PRKDCPTGES2PGR | |
| SCHEMBL18086161 | 0.87 | ALOX5 (0.54) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL20277499 | 0.87 | ALOX5 (0.57) | ALOX5GGPS1PRKDCPTGES2PRMT5 | |
| SCHEMBL31511490 | 0.87 | ALOX5 (0.56) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL15552528 | 0.87 | ALOX5 (0.56) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL21742671 | 0.85 | ALOX5 (0.50) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL18086151 | 0.84 | ALOX5 (0.51) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL24434074 | 0.82 | ALOX5 (0.40) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL15551283 | 0.82 | ALOX5 (0.42) | ALOX5GGPS1PRKDCPTGES2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10355217-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10355217-B2 | Compounds and organic electronic devices | ETV6, AFF2, CYP2C19 | ALOX5 953/4885GGPS1 576/4885PRKDC 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.