Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | PRKDC | P78527 | 4/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12324541 | 0.88 | ALOX5 (0.57) | ALOX5PRKDCGGPS1PTGES2PGR | |
| SCHEMBL20276869 | 0.88 | ALOX5 (0.59) | ALOX5PRKDCGGPS1PTGES2PGR | |
| SCHEMBL21037803 | 0.87 | ALOX5 (0.49) | ALOX5PRKDCGGPS1PTGES2PGR | |
| SCHEMBL21742872 | 0.87 | ALOX5 (0.49) | ALOX5PRKDCGGPS1PTGES2PGR | |
| SCHEMBL21742727 | 0.87 | ALOX5 (0.49) | ALOX5PRKDCGGPS1PTGES2PGR | |
| SCHEMBL21742876 | 0.87 | PDK2 (0.36) | ALOX5PGRPDK2MAOAALK | |
| SCHEMBL16017825 | 0.87 | ALOX5 (0.56) | ALOX5PRKDCGGPS1PTGES2PGR | |
| SCHEMBL21742674 | 0.86 | HPGD (0.40) | PRKDCPGRPDK2MEN1KMT2A | |
| SCHEMBL21742873 | 0.86 | MAOA (0.39) | ALOX5PGRPDK2MEN1CYP2C19 | |
| SCHEMBL21164748 | 0.85 | ALOX5 (0.47) | ALOX5PRKDCGGPS1PTGES2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | PNMT, DDT, TYR | ALOX5 2532/4885PRKDC 3014/4885GGPS1 2508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.