Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 4/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21164748 | 0.91 | ALOX5 (0.47) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL12996570 | 0.89 | ALOX5 (0.59) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL17614164 | 0.89 | ALOX5 (0.59) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL21742875 | 0.87 | PDK2 (0.38) | ALOX5PDK2ESR1ESR2ATM | |
| SCHEMBL21742676 | 0.87 | HPGD (0.38) | ALOX5PDK2PGRESR1ESR2 | |
| SCHEMBL21742871 | 0.87 | PDK2 (0.38) | ALOX5PDK2ESR1ESR2ATM | |
| SCHEMBL21742671 | 0.87 | ALOX5 (0.50) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL21742869 | 0.87 | HPGD (0.38) | ALOX5PDK2PGRESR1ESR2 | |
| SCHEMBL21742672 | 0.87 | ALOX5 (0.52) | ALOX5GGPS1PRKDCPTGES2PDK2 | |
| SCHEMBL9917134 | 0.87 | ALOX5 (0.52) | ALOX5GGPS1PRKDCPTGES2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | PNMT, DDT, TYR | ALOX5 2532/4885GGPS1 2508/4885PRKDC 3014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.