SCHEMBL21165052

SCHEMBL21165052

Cc1cc(C)c(Nc2ccc(C(c3ccc(Nc4ccccc4C)cc3)c3ccc(Nc4ccccc4C)cc3)c3ccccc23)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 11/20 0.43
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
RECQL P46063 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21165036 0.93 RAPGEF4 (0.47) RAPGEF4
SCHEMBL21165197 0.90 RAPGEF4 (0.42) RAPGEF4MEN1KMT2AKDM4EGLA
SCHEMBL21165252 0.90 RAPGEF4 (0.46) RAPGEF4MEN1KMT2AKDM4EGLA
SCHEMBL21165316 0.88 RAPGEF4 (0.43) RAPGEF4
SCHEMBL21165255 0.85 RAPGEF4 (0.46) RAPGEF4
SCHEMBL21165374 0.81 HPGD (0.46) MEN1KMT2AKDM4EGLAGAA
SCHEMBL18351164 0.80 RAPGEF4 (0.38) RAPGEF4MEN1KMT2AMAPTRECQL
SCHEMBL18351161 0.79 RAPGEF4 (0.38) RAPGEF4MEN1KMT2AMAPTRECQL
SCHEMBL21165254 0.78 RAPGEF4 (0.40) RAPGEF4KDM4EGAA
SCHEMBL18351158 0.78 RAPGEF4 (0.37) RAPGEF4MEN1KMT2AMAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 RAPGEF4 3390/4885MEN1 3357/4885KMT2A 1719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.