Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 13/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21165255 | 0.90 | RAPGEF4 (0.46) | RAPGEF4 | |
| SCHEMBL21165036 | 0.85 | RAPGEF4 (0.47) | RAPGEF4 | |
| SCHEMBL21165252 | 0.84 | RAPGEF4 (0.46) | RAPGEF4KDM4EGAA | |
| SCHEMBL21165316 | 0.81 | RAPGEF4 (0.43) | RAPGEF4 | |
| SCHEMBL21165197 | 0.80 | RAPGEF4 (0.42) | RAPGEF4HPGDKDM4EGAA | |
| SCHEMBL21165052 | 0.78 | RAPGEF4 (0.43) | RAPGEF4KDM4EGAA | |
| SCHEMBL18351164 | 0.71 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1HPGDNPC1POLB | |
| SCHEMBL21165244 | 0.71 | RAPGEF4 (0.52) | RAPGEF4 | |
| SCHEMBL21165034 | 0.70 | RAPGEF4 (0.35) | RAPGEF4 | |
| SCHEMBL18351161 | 0.70 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1HPGDPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351526-B2 | Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation | FUJIFILM CORPORATION (JP) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351526-B2 | Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation | O60361, WDR12, SEM1 | RAPGEF4 3390/4885EGFR 3082/4885ERBB2 2953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.